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. 2017 Nov 11;8(70):114924–114934. doi: 10.18632/oncotarget.22414

Figure 3. Viability of lymphoma cells with novel chemotherapy agents in combination with 9-ING-41 (Related to Table 2).

Figure 3

10,000 cells (A, F, K: Daudi; B, G, L: SUDHL-4; C, H, M: KPUM-UH1; D, I, N: Karpas 422; E, J, O: TMD8) were plated per well of a 96-well plate and treated with a dose response series of both 9-ING-41 (0-0.5 μM) and Venetoclax (0-5,000 nM) (A-E) or BAY-1143572 (0-50 μM) (F-J) or Idelalisib (0-50 μM) (K-O) in triplicate. Viability after 3 days was analyzed using the MTS assay. Briefly, 20μl of MTS reagent was added to cells and incubated for 2 hours and, the absorbance at 490 nm was read using a Biotek plate reader. Relative absorbance is calculated after setting the average absorbance of the no-treatment control as 1.