Table 3. Receiver operative characteristics (ROC) analyses.
Receiver operative characteristics analysis | EC patients vs. healthy volunteers | Hypertensive vs. non-hypertensive EC patients | Body mass index < 30 vs. ≥ 30 | Age < 65 years Vs. ≥ 65 years |
---|---|---|---|---|
area under the ROC curve (95% confidence interval) | 0,704 (0.632 to 0.777) | 0.618 (0.521-0.714) | 0.634 (0.538-0.739) | 0.584 (0.496-0,671) |
Sensitivity at the best cut-off (cfDNA=800 ng/ml) | 52.1% | 46,7% | 48,2% | 54,7% |
Specificity at the best cut-off (cfDNA=800 ng/ml) | 83.9% | 74,1% | 72,2% | 60,6% |
Receiver operative characteristics (ROC) results and optimal cut-offs values for cfDNA in G1, G2 and G3 EC sera versus those from healthy volunteers, in samples from hypertensive versus non-hypertensive EC, in those from patients with BMI ≥ 30 versus BMI < 30, and aged ≥65 versus aged < 65 years.