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. 2017 Dec 15;8(70):115315–115325. doi: 10.18632/oncotarget.23258

Figure 5. Suppression of gemcitabine-induced ISG expression by exogenous cytidine.

Figure 5

HeLa cells were treated with gemcitabine (20 μM) or IFN-α (10 ng/ml) in the presence or absence of cytidine (50 μM). After 24 hours, cellular RNAs were isolated and the expression of IFIT1 (A) and DDX58 (B) mRNAs was determined by quantitative real-time PCR. Results were normalized as a percentage relative to DMSO-treated cells. The average and standard deviation were obtained from three independent experiments. * indicates P < 0.05.