Skip to main content
. 2017 Dec 15;8(70):115398–115412. doi: 10.18632/oncotarget.23267

Table 2. Hematological parameters of nude mice bearing MKN-45 cell xenograft tumors.

Hematological parameters Normal Vehicle 5-FU 10 mg/kg CT Standard
1 mg/kg 10 mg/kg
White blood cells (109/L) 9.98±1.54 9.48±3.14 10.75±1.78 10.29±1.11 10.82±1.39 4.0-12.0
Lymphocytes percentage (%) 65.01±17.02 50±17.74 69±10.6 73.65±7.2 70.85±13.55 54.0-85.0
Middle cells percentage (%) 1.59±0.77 1.43±0.82 1.54±0.53 1.19±0.47 1.65±0.07 0.0-20.0
Granulocyte percentage (%) 33.4±6.74 27.7±8.47 19.3±5.78 16.17±7.25 22.5±3.48 12.0-44.0
Lymphocytes (109/L) 6.72±1.58 6.46±2.1 7.75±0.78 5.09±1.05 5.46±1.59 3.0-8.5
Middle cells (109/L) 0.15±0.12 0.11±0.06 0.09±0.04 0.02±0.05 0.07±0.01 0.0-2.0
Granulocyte (109/L) 2.12±1.58 3.33±1.65 2.86±1.58 4.19±1.31 2.27±2.23 0.7-5.0
Red blood cells (1012/L) 10.46±0.13 10.6±0.08 10.38±0.20 9.89±1.21 9.06±1.04 7.0-12.5
Hemoglobin (g/L) 152.57±14.16 161.25±3.77 159.45±5.26 170.15±2.99 149±15.25 100-190
Mean corpuscular volume (fL) 57.57±0.53 56.25±0.5 56.55±0.52 56.38±0.65 55.5±0.71 51.0-65.0
Hematokrit (L/L) 0.5±0.01 0.49±0.03 0.48±0.01 0.51±0.01 0.46±0.05 0.35-0.55
Mean corpuscular hemoglobin (Pg) 18.1±5.57 19.8±1.27 20.01±0.36 18.93±1.74 18±1.41 12.0-30.0
Mean corpuscular hemoglobin concentration (g/L) 314.86±6.89 285.75±3.86 295±6.93 270.62±13.18 301.5±10.51 230-330
Red blood cell distribution width_SD (fL) 41.4±0.27 40.63±0.39 40.85±0.41 40.3±1.19 39.15±2.05 15.0-55.0
Red blood cell distribution width_CV (%) 21.83±0.08 21.93±0.13 21.9±0.09 21.68±0.43 21.25±0.78 12.0-30.0
Blood platelet (109/L) 186.29±34.43 144.25±29.96 218.91±21.02 214.38±47.93 200.5±54.45 100-300
Mean platelet volume (fL) 6.67±0.7 6.95±0.49 7.25±0.33 7.1±0.81 7.2±0.57 6.1-12.0
Thrombocytocrit (L/L) 0.12±0.04 0.1±0.03 0.16±0.02 0.15±0.04 0.14±0.03 0.10-0.60
Platelet distribution width (%) 15.89±0.37 15.15±0.21 15.46±0.24 15.67±0.35 15.14±0.37 1.0-30.0

Note: Blood samples were taken after CT or 5-FU treatment for 20 days.