Table 1. Levels of inflammation and oxidative stress related factors at 48 h after MCAO in each group. Data are expressed as means ± SD (n = 8).
GROUPS | TNF-α | IL-1β | IL-6 | Sod | GSH-Px | MDA |
---|---|---|---|---|---|---|
(Pg/ml) | (Pg/ml) | (Pg/ml) | (U/mg) | (U/mg) | (μmol/mg) | |
Sham | 57.6 ± 2.3 | 15.5 ± 1.2 | 65.6 ± 4.3 | 163.4 ± 9.5 | 73.1 ± 7.4 | 36.5± 8.7 |
Model | 212.3 ± 13.8** | 56.2 ± 3.1** | 272.1 ± 10.8** | 88.6 ± 8.4** | 49.6 ± 4.7** | 63.6± 13.5** |
DSS | 113.2 ± 12.0#,* | 30.6 ± 3.4#,* | 133.9 ± 11.1#,* | 129.3 ± 9.7#,* | 63.8 ± 7.5#,* | 45.38± 8.7#,* |
HSYA | 114.7 ± 12.7#,* | 27.6 ± 2.1#,* | 124.7 ± 2.7#,* | 121.9 ± 12.1#,* | 57.4 ± 4.9#,* | 53.02± 12.5#,* |
DSS+HSYA | 79.4 ± 6.1# | 20.1 ± 3.3# | 89.4 ± 6.1# | 145.3 ± 5.5# | 71.1±4.1# | 41.60± 7.1# |
# P < 0.05 vs. model group; * P < 0.05 vs. DSS+ HSYA group. ** P < 0.01 vs. Sham.