Table 3. Correlation between rs80292941 polymorphism and TB phenotype traits.
Characterizations | AA (N=380) | AT + TT (N=96) | P |
---|---|---|---|
Clinical phenotypes n (%) | |||
Systemic symptoms | |||
Fever | 170 (80.2) | 42 (43.75) | 0.862 |
Weight loss | 128 (40.76) | 32 (33.33) | 0.948 |
Night sweat | 111 (32.48) | 19 (19.79) | 0.064 |
Poor appetite | 136 (38.22) | 30 (31.25) | 0.404 |
Fatigue | 92 (38.22) | 18 (18.75) | 0.257 |
Local chest symptoms | |||
cough | 242 (57.76) | 65 (67.71) | 0.462 |
hemoptysis | 59 (14.29) | 13 (13.54) | 0.628 |
chest pain | 68 (34.16) | 17 (17.71) | 0.966 |
dyspnea | 20 (7.45) | 4 (4.17) | 0.859 |
Laboratory traits | |||
Full blood cell counts | |||
Erythrocyte (×1012/L) | 4.18 ± 0.84 | 4.28 ± 0.76 | 0.295 |
Hematocrit (%) | 37.00 (32.00−41.00) | 38.00 (32.00−42.00) | 0.471 |
Hemoglobin (g/L) | 118.10 ± 24.40 | 119.36 ± 23.56 | 0.647 |
Platelets (×109/L) | 252.18 ± 118.75 | 247.86 ± 114.22 | 0.749 |
Leucocytes (×109/L) | 6.49 (4.80−8.90) | 6.29 (4.73−8.63) | 0.362 |
Neutrophils (×109/L) | 4.64 (3.15−6.58) | 4.19 (3.01−6.26) | 0.172 |
Lymphocytes (×109/L) | 1.07 (0.75−1.52) | 1.25 (0.79−1.71) | 0.152 |
Monocytes (×109/L) | 0.46 (0.31−0.67) | 0.45 (0.29−0.62) | 0.407 |
Routine TB markers | |||
CRP (mg/L) | 22.35 (7.63−76.85) | 19.35 (6.81−69.25) | 0.214 |
ESR (mm/h) | 45.00 (23.00−73.00) | 43.00 (22.00−74.00) | 0.824 |
TB etiological assays | |||
Positive TB-DNA | 136 (55.28) | 37 (58.73) | 0.623 |
Positive smear | 111 (31.18) | 29 (32.22) | 0.849 |
CT scanning | |||
Bilateral lung lesion | 191 (66.55) | 55 (75.34) | 0.204 |
Unilateral lung lesion | 86 (29.97) | 17 (23.29) |