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. 2017 Dec 14;8(70):115596–115608. doi: 10.18632/oncotarget.23313

Figure 2. Effects of Sur8 level on FGF2-induced cellular transformation and migration.

Figure 2

(A) DLD-1 control (CON), Sur8-knockout (Sur8-KO) cells and SW480-CON, or stably expressing GFP-Sur8 (Sur8-OE) cells were treated with PBS (control) or FGF2 for 24 hours. WCEs were immunoblotted with the indicated antibodies. (B-D) After treating DLD-1 and SW480 cell lines as indicated, bioassays for measuring cell proliferation rate (B), foci-forming ability (C), and migration rate (D) were performed. All graphs represent mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001. Scale bars, 500 μm.