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. 2017 Dec 18;8(70):115632–115646. doi: 10.18632/oncotarget.23361

Figure 3. Reovirus enhanced TRAIL and Fas expression in GIST-T1 and GIST-IR cells.

Figure 3

(A) Western blot analysis showed changes in apoptosis-related proteins, TRAIL, cell surface death receptors (DR) 4, DR5, Fas ligand, Fas, caspase-3, and poly ADP ribose polymerase (PARP) in GIST-T1 and GIST-IR cells following treatment with 10 MOI of reovirus for 72 or 96 hours. (B) Relative expression of TRAIL and FAS proteins in GIST-T1 and GIST-IR with or without 10 MOI of reovirus for 96 hours quantified by densitometry using imageJ software. Each result represents the mean ± SD of three experiments. *P<0.01, compared to controls.