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. Author manuscript; available in PMC: 2018 Jan 22.
Published in final edited form as: J Alzheimers Dis. 2017;58(2):401–411. doi: 10.3233/JAD-160965

Table 5a.

Summary of the Block Design (WAIS-IV) Total Score (mITT Population)

Score Placebo
(N=6)		 ELND005 250 mg BID
(N=12)		 ELND005 250 mg QD
(N=4)
Baseline
 Mean (SD) 14.7 (6.0) 15.6 (11.8) 19.0 (17.9)
 Median 16.0 11.0 13.0
 Range 8.0–24.0 0.0–37.0 6.0–44.0
Week 4
 Mean (SD) 14.7 (5.5) 16.5 (10.4) 21.3 (20.8)
 Median 14.0 20.0 14.0
 Range 8.0–24.0 0.0 – 29.0 6.0–51.0
Week 4 CFB
 Mean (SD) 0.0 (4.4) 0.9 (6.8) 2.3 (11.1)
 Median 0.0 0.0 3.5
 Range −8.0-4.0 −13.0 – 16.0 −12.0 – 14.0

CFB = Change from baseline, SD= Standard Deviation