Table 5b.

Summary of the VABS-II Total Score (mITT Population)

VABS-II Score	Placebo (N=6)	ELND005 250 mg BID (N=12)	ELND005 250 mg QD (N=4)
Baseline
Mean (SD)	682.3 (60.9)	660.5 (49.1)	690.0 (31.8)
Median	687.0	666.0	691.0
Range	597.0–775.0	550.0–736.0	652.0–726.0
Week 4
Mean (SD)	674.3 (48.9)	672.6 (53.7)	683.3 (32.0)
Median	689.5	659.5	681.5
Range	594.0–716.0	565.0–749.0	650.0–720.0
Week 4 CFB
Mean (SD)	−8.0 (26.0)	12.1 (31.2)	−6.8 (32.7)
Median	0.5	12.5	3.0
Range	−59.0 – 13.0	−25.0–82.0	−53–20.0