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Summary of the RADD-2 Total Score (mITT Population)
| RADD Total Score (calculated) | Placebo (N=6) |
ELND005 250 mg BID (N=12) |
ELND005 250 mg QD (N=4) |
|---|---|---|---|
|
| |||
| Baseline | |||
| Mean (SD) | 62.2 (9.8) | 58.7 (10.2) | 58.0 (15.6) |
| Median | 66.5 | 61.5 | 63.0 |
| Range | 49.0–73.0 | 43.0–70.0 | 36.0–70.0 |
|
| |||
| Week 4 | |||
| Mean (SD) | 62.8 (10.3) | 59.1 (11.5) | 64.3 (13.5) |
| Median | 65.0 | 62.5 | 70.5 |
| Range | 49.0–75.0 | 35.0–72.0 | 44.0–72.0 |
|
| |||
| Week 4 CFB | |||
| Mean (SD) | 0.7 (2.3) | 0.4 (4.3) | 6.3 (4.6) |
| Median | 0.5 | 1.0 | 5.5 |
| Range | –3.0–4.0 | −8.0–8.0 | 2.0–12.0 |
