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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Hippocampus. 2018 Jan 10;28(2):178–185. doi: 10.1002/hipo.22820

Figure 4.

Figure 4

(A) The proportion of Arc mRNA-positive granule cells is significantly higher in the suprapyramidal blade (SPB) of dorsal dentate gyrus following exploratory behavior (2.5% +/− 0.2) as compared to the suprapyramidal blade of the ventral dentate gyrus (1.2% +/− 0.1). (B) Confocal images taken from the dorsal and ventral suprapyramidal blades of the dentate gyrus (left panels) and infrapyramidal blades of the dentate gyrus (right panels). A significant difference was observed between behavior-treated animals and caged control rats in the suprapyramidal blade of dentate gyrus. No significant difference was observed between behavior-treated animals and caged control rats in the infrapyramidal blade (IPB) of dentate gyrus. Calibration bar = 20 µm. Arc mRNA- positive cells are shown in red and granule cell nuclei are counterstained with Sytox, shown in blue. The insets in B show a magnified view of the Arc transcription foci in granule cells in the dorsal and more ventral areas respectively. The white arrows correspond to the same cell in the main image and the magnified image.