. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: Liver Int. 2017 Jul 21;38(2):239–247. doi: 10.1111/liv.13501

Table 2.

Unadjusted and adjusted annual percentage change and join-points for hepatitis C-related outcomes.

Annual percentage change (APC)	First segment		Second segment
	Interval		Interval
	APC (95%CI)	p-value	APC (95%CI)	p-value
Cirrhosis	2006≤2015
Unadjusted	2.7 (2.1, 3.2)	<0.01
Adjusted	1.2 (0.7, 1.8)	<0.01
Decompensated Cirrhosis	2006≤2015
Unadjusted	1.5 (0.7, 2.4)	<0.01
Adjusted (<40)	−3.7 (−11.9, 5.3)	0.40
Adjusted (40<50)	−7.9 (−10.9, −4.8)	<.0001
Adjusted (50<60)	−3.2 (−4.4, −1.9)	<.0001
Adjusted (≥60)	1.5 (0.2, 2.8)	0.02
All-cause Mortality	2006<2010		2010≤2015
Unadjusted	13.7 (9.4, 18.1)	<0.01	−1.6 (−4.4, 1.3)	0.28
Adjusted	9.6 (5.5, 13.8)	<0.01	−5.2 (−7.9, −2.4)	<0.01