Table 4. Multivariate logistic regression model to assess the associations between uterine leiomyoma and VTE after excluding the patients with hormone therapy and cancer diagnosis in uterine leiomyoma comparison.
VTE case# | Control | Adjusted odds ratioModel 1 (95 % CI) | p value | Adjusted odds ratioModel 2 (95 % CI) | p value | |
Before matching data | ||||||
Non-leiomyoma | 1539 (95.47%) | 348283 (95.97%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 73 (4.53%) | 14623 (4.03%) | 1.632 (1.283-2.076) | < 0.0001 | 1.579 (1.245-2.003) | 0.0002 |
Frequency matching data | ||||||
Non-leiomyoma | 1539 (95.47%) | 7523 (96.61%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 73 (4.53%) | 264 (3.39%) | 1.615 (1.220-2.137) | 0.0008 | 1.650 (1.256-2.168) | 0.0003 |
Propensity score matching data | ||||||
Non-leiomyoma | 1518 (95.47%) | 6249 (96.35%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 72 (4.53%) | 237 (3.65%) | 1.387 (1.056-1.823) | 0.0188 | 1.341 (1.023-1.758) | 0.0334 |
Model 1 adjusted for uterine leiomyoma and the significantly different variables in Table 1. Model 2 adjusted for uterine leiomyoma, age and propensity score.
VTE, venous thromboembolism.