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Table 4. Multivariate logistic regression model to assess the associations between uterine leiomyoma and VTE after excluding the patients with hormone therapy and cancer diagnosis in uterine leiomyoma comparison.

VTE case# Control Adjusted odds ratioModel 1 (95 % CI) p value Adjusted odds ratioModel 2 (95 % CI) p value
Before matching data
 Non-leiomyoma 1539 (95.47%) 348283 (95.97%) 1 (reference) 1 (reference)
 Leiomyoma* 73 (4.53%) 14623 (4.03%) 1.632 (1.283-2.076) < 0.0001 1.579 (1.245-2.003) 0.0002
Frequency matching data
 Non-leiomyoma 1539 (95.47%) 7523 (96.61%) 1 (reference) 1 (reference)
 Leiomyoma* 73 (4.53%) 264 (3.39%) 1.615 (1.220-2.137) 0.0008 1.650 (1.256-2.168) 0.0003
Propensity score matching data
 Non-leiomyoma 1518 (95.47%) 6249 (96.35%) 1 (reference) 1 (reference)
 Leiomyoma* 72 (4.53%) 237 (3.65%) 1.387 (1.056-1.823) 0.0188 1.341 (1.023-1.758) 0.0334

Model 1 adjusted for uterine leiomyoma and the significantly different variables in Table 1. Model 2 adjusted for uterine leiomyoma, age and propensity score.

VTE, venous thromboembolism.