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Supplementary Table 2. Multivariate logistic regression model to assess the associations between uterine leiomyoma and VTE. We carried out a sensitivity analysis in diagnosis of uterine leiomyoma and VTE identified using a stringent criterion. The analysis showed that the association between uterine leiomyoma and VTE was in agreement with the results in Table 2. Sensitivity table:

VTE case# Control Adjusted odds ratioModel 1 (95 % CI) p-value Adjusted odds ratioModel 2 (95 % CI) p-value
Before matching data
 Non-leiomyoma 1550 (96.15%) 377760 (96.05%) 1 (reference) 1 (reference)
 Leiomyoma* 62 (3.85%) 15524 (3.95%) 1.417 (1.087-1.846) 0.01 1.444 (1.107-1.883) 0.0067
Frequency matching data
 Non-leiomyoma 1550 (96.15%) 6243 (96.82%) 1 (reference) 1 (reference)
 Leiomyoma* 62 (3.85%) 205 (3.18%) 1.645 (1.190-2.274) 0.0026 1.371 (1.015-1.851) 0.0397
Propensity score matching data
 Non-leiomyoma 1536 (96.3%) 6158 (97.13%) 1 (reference) 1 (reference)
 Leiomyoma* 59 (3.7%) 182 (2.87%) 1.456 (1.071-1.979) 0.0164 1.464 (1.081-1.982) 0.0137

Model 1 adjusted for uterine leiomyoma and the significantly different variables in Table 1. Model 2 adjusted for uterine leiomyoma, age and propensity score.

* The diagnosis of leiomyoma was confirmed by gynecologic ultrasound. # The diagnosis of VTE was confirmed using patients received anticoagulation therapy.

VTE, venous thromboembolism.