Supplementary Table 2. Multivariate logistic regression model to assess the associations between uterine leiomyoma and VTE. We carried out a sensitivity analysis in diagnosis of uterine leiomyoma and VTE identified using a stringent criterion. The analysis showed that the association between uterine leiomyoma and VTE was in agreement with the results in Table 2. Sensitivity table:
VTE case# | Control | Adjusted odds ratioModel 1 (95 % CI) | p-value | Adjusted odds ratioModel 2 (95 % CI) | p-value | |
Before matching data | ||||||
Non-leiomyoma | 1550 (96.15%) | 377760 (96.05%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 62 (3.85%) | 15524 (3.95%) | 1.417 (1.087-1.846) | 0.01 | 1.444 (1.107-1.883) | 0.0067 |
Frequency matching data | ||||||
Non-leiomyoma | 1550 (96.15%) | 6243 (96.82%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 62 (3.85%) | 205 (3.18%) | 1.645 (1.190-2.274) | 0.0026 | 1.371 (1.015-1.851) | 0.0397 |
Propensity score matching data | ||||||
Non-leiomyoma | 1536 (96.3%) | 6158 (97.13%) | 1 (reference) | 1 (reference) | ||
Leiomyoma* | 59 (3.7%) | 182 (2.87%) | 1.456 (1.071-1.979) | 0.0164 | 1.464 (1.081-1.982) | 0.0137 |
Model 1 adjusted for uterine leiomyoma and the significantly different variables in Table 1. Model 2 adjusted for uterine leiomyoma, age and propensity score.
* The diagnosis of leiomyoma was confirmed by gynecologic ultrasound. # The diagnosis of VTE was confirmed using patients received anticoagulation therapy.
VTE, venous thromboembolism.