Table 3.
Presenting features, initial IgG4 levels, treatment, and follow up PET/CT findings
Patient no. | Presenting features | IgG4 levels at the time of diagnosis (mg/dL) | Latest subsequent IgG4 levels (mg/dL) | Initial prednisolone dose or any other medication | Current prednisolone dose or any other medication | Follow-up scan findings |
---|---|---|---|---|---|---|
1 | Loss of weight, fatigue | 269 | 340 (4 years post diagnosis) |
50 mg OM | 7.5 mg OM | Abnormal (4 years post diagnosis) |
2 | Paraproteinaemia, loss of weight, altered bowel habits | 22 | 159 (3 years post diagnosis) |
30 mg BD; Rituximab; Mycofenolate mofeteil 1 g BD |
5 mg OM | Normal (3 years post diagnosis) |
3 | Enlargement of salivary glands and loss of weight | 51 | 193 (1 year post diagnosis) |
80 mg OM | 5 mg OM; mycofenolate mofeteil 1 g BD | Normal (1 year post diagnosis) |
4 | Chest pain | 149 | 158 (1 year post diagnosis) |
30 mg OM; Methotrexate 20 mg once/week |
3 mg OM; methotrexate 15 mg once/week |
Normal (2 years post diagnosis) |
5 | Bilateral lacrimal gland enlargement | 269 | 340 (1 year post diagnosis) |
Nil | Nil | N/A |
6 | Obstructive jaundice | 233 | 340 (5 months post diagnosis) |
2 mg 4 times/week; Azathioprine 100 mg OM |
5 mg OM; azathioprine 150 mg OM |
N/A |
7 | Loss of weight | 128 | Nil | 5 mg OM | 5 mg OM | N/A |
8 | Increasing size of cervical nodes | 233 | 340 (4 months post diagnosis) |
40 mg OM | 5 mg OM | N/A |
9 | Orbital mass, left optic neuropathy, salivary gland enlargement | 52 | Nil | 60 mg OM | Nil | N/A |
10 | Obstructive jaundice, loss of weight | 340 | Nil | 30 mg OM | 20 mg OM | N/A |
11 | Obstructive jaundice | 285 | 224 (3 years post diagnosis) |
5 mg BD | 5 mg EOD | N/A |
12 | Pancreatitis | 126 | Nil | Nil | Nil | N/A |
OM: once in the morning
EOD: every other day
BD: twice daily