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. 2018 Jan 22;8:1364. doi: 10.1038/s41598-018-19470-3

Table 2.

Association between radiographic knee OA and the presence of frequent knee pain in five racial/ethnic populationsa.

Racial/ethnic origin (study) Frequent knee pain Kellgren and Lawrence grade
0 1 2 3–4
Urban Chinese No 141 (56.0) 48 (19.0) 38 (15.1) 25 (10.0)
(BOA) Yes 113 (44.8) 54 (21.4) 38 (15.1) 47 (18.7)
OR (95% CI) 1 1.9 (0.9, 3.7) 6.8 (2.6, 17.8) 16.8 (5.3, 53.2)
Rural Chinese No 194 (87.8) 9 (4.1) 14 (6.3) 4 (1.8)
(WOA) Yes 180 (81.4) 12 (5.4) 22 (10.0) 7 (3.2)
OR (95% CI) 1 2.1 (0.9, 5.0) 3.8 (1.1, 12.9) 9.4 (1.7, 52.5)
Japanese No 27 (9.1) 87 (29.3) 126 (42.4) 57 (19.2)
(ROAD) Yes 23 (7.7) 62 (20.9) 111 (37.4) 101 (34.0)
OR (95% CI) 1 1.1 (0.3, 3.9) 3 (0.8, 11.6) 24.2 (4.8, 121.8)
Koreans No 32 (32.7) 41 (41.8) 20 (20.4) 5 (5.1)
(HAS) Yes 25 (25.5) 37 (37.8) 28 (28.6) 8 (8.2)
OR (95% CI) 1 2.3 (0.9, 6.0) 6.6 (1.7, 26.2) 10 (2.0, 49.9)
African-Americans No 75 (35.4) 36 (17.0) 73 (34.4) 28 (13.2)
(OAI) Yes 57 (26.9) 28 (13.2) 75 (35.4) 52 (24.5)
OR (95% CI) 1 1.7 (0.9, 3.3) 3.5 (1.7, 7.3) 8.5 (3.6, 20.3)
Caucasians No 358 (42.9) 197 (23.6) 179 (21.4) 101 (12.1)
(OAI) Yes 249 (29.8) 142 (17.0) 183 (21.9) 261 (31.3)
OR (95% CI) 1 1.8 (1.3, 2.4) 3.7 (2.6, 5.1) 15.8 (10.1, 24.8)

N(%), Abbreviations: CI, Confidence interval.

Conditional logistic regression results for subjects with knees discordant for the presence of frequent knee pain.

Subjects included in Table 2 with bilateral knee pain of discrepant severity (in the HAS and OAI studies) were excluded.

Abbreviations: BOA, Beijing Osteoarthritis Study, China; WOA, Wuchuan Osteoarthritis Study, China; ROAD, Research on Osteoarthritis/osteoporosis Against Disability Study, Japan; HAS, Hallym Aging Study, South Korea; OAI, Osteoarthritis Initiative, United States; OR, odds ratio; CI, confidence interval.