Table 2.
The results of family-based association test between rs2248359 and T2DM.
| Model | Allele | afreq | Fam# | S-E(S) | Var(S) | Z | P |
|---|---|---|---|---|---|---|---|
| Additive | C | 0.617 | 16 | −5 | 6 | −2.041 | 0.041227 |
| T | 0.383 | 16 | 5 | 6 | 2.041 | 0.041227* | |
| Dominant | T | 0.383 | 13 | 5 | 3.375 | 2.722 | 0.006496* |
| Recessive | C | 0.617 | 13 | −5 | 3.375 | −2.722 | 0.006496 |
Note: 232 pedigrees containing 280 T2DM patients were read in FBAT software. S-E(S) and Var (S) are the expected value and variance of the test statistic. Z: the test statistic; P: significance level. *The significant association between allele and T2DM (Z > 0 and P < 0.05).