Table 2.
RT for the silenced genes in different cell cycle phases and their cumulative PDT were determined in hours. PLK1 and Akt1 were employed as positive controls for cell cycle arrest. NS siRNA treated sample represented the negative control.
Samples | RT G1 | RT S | RT G2 | PDT (total of RT) |
---|---|---|---|---|
NS siRNA(Control) | 16.82 | 4.66 | 5.01 | 26.49 |
EIF2A | 24.81 | 8.13 | 9.15 | 42.09 |
ERH | 22.54 | 6.41 | 6.3 | 35.25 |
IRS4 | 21.55 | 6.91 | 6.03 | 34.49 |
MYH9 | 21.48 | 6.41 | 5.8 | 33.69 |
SPTBN2 | 19.67 | 6.13 | 6.98 | 32.79 |
KPNB1 | 18.61 | 4.8 | 8.12 | 31.52 |
ACTB | 16.92 | 6.04 | 8.32 | 31.29 |
SARNP | 16.09 | 5.66 | 8.8 | 30.55 |
DBN1 | 17.61 | 4.85 | 7.9 | 30.36 |
NOTCH2 | 19.21 | 5.71 | 5.44 | 30.35 |
CDK1 | 14.42 | 6.41 | 8.71 | 29.54 |
HNRNPDL | 15.37 | 5.51 | 8.39 | 29.27 |
ANXA6 | 17.91 | 6.3 | 4.59 | 28.81 |
SMNDC1 | 17.49 | 5.83 | 5.32 | 28.64 |
CCNB1 | 14.51 | 6.03 | 7.95 | 28.49 |
STOML2 | 17.86 | 5.61 | 4.84 | 28.32 |
SLC25A5 | 17.92 | 5.04 | 4.72 | 27.68 |
HDGF | 15.38 | 5 | 6.23 | 26.61 |
CORO1C | 12.76 | 6.17 | 6.91 | 25.84 |
NUCKS1 | 11.36 | 4.77 | 7.21 | 23.34 |
RBM3 | 12.88 | 3.55 | 5.56 | 21.99 |
MYO1 | 11.61 | 3.91 | 6.01 | 21.53 |
EPPK1 | 7.66 | 2.6 | 4.25 | 14.51 |