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. 2018 Jan 22;8:1320. doi: 10.1038/s41598-017-18335-5

Table 1.

Pathways that involve differentially expressed proteins in SYFs of layer-type L2 strain Taiwan country chickens after acute heat stress.

KEGG pathway Related proteins and their expression in chicken SYF after heat stress#
Apoptosis PIK3CG (NS,↑,↑); TUBA1C (NS,↑,↑); ACTG1 (NS,↑,↑)
Carbon metabolism ENO1 (NS,↑,↑); GAPDH (NS,↑,↑); TPI1 (NS,↑,↑)
Gap junction TUBA1C (NS,↑,↑); TUBB2A (NS,↑,↑); TUBB2B (NS,↑,↑); TUBB4B (NS,↑,↑)
Glycolysis/Gluconeogenesis ENO1 (NS,↑,↑); GAPDH (NS,↑,↑); TPI1 (NS,↑,↑)
Inositol phosphate metabolism TPI1 (NS,↑,↑); PIK3CG (NS,↑,↑)
Oxidative phosphorylation ATP5A1W (NS,↑,↑); ATP5A1W (NS,↑,↑); ATP5B (↓,↑,↑); NDUFA10 (NS,↑,↑)
Metabolic pathways ENO1 (NS,↑,↑); GAPDH (NS,↑,↑); TPI1 (NS,↑,↑); ATP5A1W (NS,↑,↑); ATP5A1W (NS,↑,↑); ATP5B (↓,↑,↑); NDUFA10 (NS,↑,↑)
Peroxisome SOD2 (NS,↑,↑); PRDX1 (NS,↑,↑)
Progesterone-mediated oocyte maturation PIK3CG (NS,↑,↑)
Proteasome PSMA5 (NS,↑,↑)
Protein processing in endoplasmic reticulum CKAP4 (↑,↑,↑); ERP29 (NS,↑,NS);HSP70 (NS,↑,↑); P4HB (NS,↑,↑); TXNDC5 (NS,↑,↑)
Regulation of actin cytoskeleton PIK3CG (NS,↑,↑); ACTG1 (NS,↑,↑); CTC-554D6.1 (NS,↑,↑)
Ribosome RPLP0 (NS,↑,NS)
RNA degradation ENO1 (NS,↑,↑); HSPD1 (↑,↑,↑); HSPA9 (NS,↑,↑)
Tight junction ACTG1 (NS,↑,↑)
Specific signaling pathway
  mTOR signaling pathway PIK3CG (NS,↑,↑)
  Toll-like receptor signaling pathway PIK3CG (NS,↑,↑)
  Wnt signaling pathway CTC-554D6.1 (NS,↑,↑)

#(H4R0/CTL, H4R2/CTL, H4R6/CTL), ↑, with an increase after heat stress; ↓, with a decrease after heat stress.