Table 1.

Summary of data collected among enrolled children at each study visit

Enrolment visit (hospital discharge)	3-month follow-up visit	6-month follow-up visit	Unscheduled visits
Questionnaire of sociodemographic, clinical history, treatments prescribed in hospital and at discharge, hospitalisation costs, dietary factors, household factors and environmental exposures. Physical exam. Anthropometry. Abstraction of medical records if available. Heel/finger prick (HIV and malaria). Stool collection (Shigella, Salmonella, Campylobacter, Escherichia coli, Cryptosporidium and Giardia). Nasopharyngeal swab collection (Streptococcus pneumoniae).	Questionnaire of study drug administration and reported illnesses, hospitalisation costs if rehospitalised, change in clinical history and treatments since last visit. Physical exam. Anthropometry. Abstraction of medical records if available (if rehospitalised). Verbal autopsy (or abstracted medical records). Heel/finger prick (HIV and malaria). Stool collection (Shigella, Salmonella, Campylobacter, E. coli, Cryptosporidium and Giardia). Nasopharyngeal swab collection (S. pneumoniae).	Questionnaire of reported illnesses, hospitalisation costs if rehospitalised, change in clinical history and treatments since last visit. Physical exam. Anthropometry. Abstraction of medical records if available (if rehospitalised). Verbal autopsy (or abstracted medical records). Heel/finger prick (HIV and malaria, sickle cell). Stool collection (Shigella, Salmonella, Campylobacter, E. coli, Cryptosporidium and Giardia). Nasopharyngeal swab collection (S. pneumoniae).	Questionnaire of reported illnesses since last scheduled visit, change in clinical history and treatments since last visit. Abstraction of medical records if available (if rehospitalised). Verbal autopsy (or abstracted medical records).