Table 2.
Previously described pluripotency markers (gene names) identified in our study in three stem cell lines: hESC (H9) and hiPSCs (SB5-MP1 and iNC-01) by ESI-MSe, MALDI-TOF/TOF or both. Markers shown in red were up-regulated in both hiPSCs vs. parental somatic cells by ESI-MSe quantification.
| Identified exclusively by ESI– MSe |
Identified exclusively by MALDI– TOF/TOF |
Identified by both MS techniques |
||||
|---|---|---|---|---|---|---|
| AIBP | SMAD4 | ADCY2 | FGFR2 | SOX15 | ACTC1 | RIF1 |
| APOE | STAT3 | APC | FINC | TBX3 | ACTG2 | SALL4 |
| APOO | VSNL1 | BBS9 | GAB1 | TERT | ALPL | SERPIN B9 |
| BRIX | BCL9 | GPC6 | TGFBR1 | AXA2L | SFN | |
| CDK1 | BCL9L | GSK3A | TP53 | CALR | SMAD3 | |
| CTNNB1 | BMP2 | JAK3 | WWP2 | CXADR | TFR1 | |
| GNAS2 | BUB1 | LAD1 | DNMT3B | TPM1 | ||
| HP1–beta | CHD1 | MEF2A | DPPA4 | TUBB3 | ||
| GRB2 | CHD7 | NR2F6 | FGFR4 | |||
| KRAS | CLU | NRK | FUBP3 | |||
| MANF | CNOT3 | PDFGA | GMFB | |||
| MAPK2K2 | CNTNAP2 | PIK3C2A | GNAS | |||
| MFGM | COIA1 | PIK3C2B | GPC4 | |||
| MIF | DAG1 | PIK3R2 | HDAC2 | |||
| NEFM | DCX | PXDN | HDGF | |||
| NEST | DMD | RARA | IGF2BP1 (IMP1) | |||
| P3H1 | EHMT1 | RB1 | LAMC1 | |||
| PODXL (Tra–1–60) | EHMT2 | S1PR1 | LIN28 | |||
| RRAS2 | EP300 | SMAD2 | MAPK1 | |||
| SHC1 | FAT3 | SOX2 | PRDX4 | |||