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. 2017 Dec 4;46(2):558–567. doi: 10.1093/nar/gkx1220

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Average normalized binding energy (4) as a function of the distance r from the target. The curve labeled TFBS at actual position displays computed over the whole set of 1544 unique target sequences in the DB (see ‘Materials and Methods’ section). The other curve represents the computed with TFBS at randomized positions (as labeled) on the DNA. The randomized coordinates are drawn with uniform probability on the DNA, with the only constraint of being at least 1000 bp away from any other target sequence in the DB.

Inline graphic — Average normalized binding energy (4) as a function of the distance r from the target. The curve labeled TFBS at actual position displays computed over the whole set of 1544 unique target sequences in the DB (see ‘Materials and Methods’ section). The other curve represents the computed with TFBS at randomized positions (as labeled) on the DNA. The randomized coordinates are drawn with uniform probability on the DNA, with the only constraint of being at least 1000 bp away from any other target sequence in the DB.