Table 1. Summary of the methods that have been attempted or proposed for preventing artificial surface fouling from infectious or thrombotic causes.
Infection prevention methods |
Antibiotic infusion |
Minocycline (16-18) |
Rifampin (16-18) |
Catheter materials |
Polytetrafluoroethylene (21) |
Polyurethane (21) |
Antiseptic coating |
Chlorhexidine (19,20) |
Sulfadiazine (19,20) |
Other |
Silver (11) |
Heparin (16) |
Thrombosis prevention methods |
Hydrophilic polymers |
Polyethylene glycol (49) |
Zwitterionic materials |
Phosphorylcholines (51,52) |
Other coatings |
Pyrolytic carbon (55-57) |
Albumin (62) |
Heparin (65) |
Direct thrombin inhibitors (71-73) |
Sirolimus (74) |
SLIPs (77-81) |
Micropatterning |
Lotus leaf conical cells (85) |
Shark skin microgrooves (86) |