Table 2. Statin and VTE related studies 2013–2016.
Year | Title | Patients | Statin | Statin use outcome |
---|---|---|---|---|
2016 | Effects of rosuvastatin as an adjuvant treatment for deep vein thrombosis | 234 | Rosuvastatin | Decreased CRP levels and decreased PTS incidence |
2016 | The association of statin therapy with the risk of recurrent venous thrombosis | 2,798 | Multiple | Decreased recurrent VTE by 26% |
2016 | Platelet reactivity in patients with venous thrombosis who use rosuvastatin: a randomized controlled clinical trial | 50 | Rosuvastatin | No effect on platelet reactivity |
2016 | Use of statins and reduced risk of recurrence of VTE in an older population. A population-based cohort study | 25,681 | Multiple | Decreased recurrent VTE by 26% |
2015 | Is lipid lowering therapy an independent risk factor for venous thromboembolism? A population-based case-control study | 2,878 | Multiple | Lipid lowering therapy (statin + non-statin) decreased VTE |
2015 | Patterns, risk factors and treatment associated with PICC-DVT in hospitalized adults: A nested case-control study | 909 | Multiple | Decreased PICC associated DVT |
2014 | Concurrent use of statins and hormone therapy and risk of venous thromboembolism in postmenopausal women: a population-based case-control study | 955,582 | Multiple | Decreased VTE regardless of hormone therapy |
2014 | Perioperative pleiotropic statin effects in general surgery | 7,777 | Multiple | Decreased perioperative VTE |
2014 | The association of statin use with reduced incidence of venous thromboembolism: a population-based cohort study | 8,082 | Multiple | Decreased VTE with relative risk of 0.60 |
2014 | Statins are associated with low risk of venous thromboembolism in patients with cancer: a prospective and observational cohort study | 1,434 | Multiple | Decreased VTE in cancer patients |
2014 | Statin use and venous thromboembolism recurrence: a combined nationwide cohort and nested case-control study | 27,862 | Multiple | Decreased recurrent VTE; high potency with more effect |
2014 | Statins, aspirin and risk of venous thromboembolic events in breast cancer patients | 3,585 | Multiple | No change in VTE in breast cancer patients |
2014 | Statins, aspirin and risk of thromboembolic events in ovarian cancer patients | 1,746 | Multiple | No change in VTE in ovarian cancer patients |
2014 | Influence of statin use on the incidence of recurrent venous thromboembolism and major bleeding in patients receiving rivaroxaban or standard anticoagulant therapy | 9,468 | Multiple | Decreased VTE by 24% |
2013 | The association between statin therapy during intensive care unit stay and the incidence of venous thromboembolism: a propensity score-adjusted analysis | 798 | Multiple | No change in VTE in ICU patients |
2013 | Statin treatment and the risk of recurrent pulmonary embolism | 3,093 | Multiple | Decreased PE by 50% |
2013 | Statin treatment and risk of recurrent venous thromboembolism: a nationwide cohort study | 44,330 | Multiple | Decreased recurrent VTE by 26% |
VTE, venous thromboembolism; CRP, C-reactive protein; PTS, post-thrombotic syndrome; PICC, peripherally inserted central catheter; DVT, deep venous thrombosis; PE, pulmonary embolism.