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. 2017 Dec 8;46(2):972–984. doi: 10.1093/nar/gkx1213

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — hCtc1(OB) deletion leads to telomere length elongation. (A) Southern blot analysis of 293T cells expressing shCtc1 and WT or mutant (double or deletion) hCtc1 genes. DNA from 0, 3, 6 and 9 passages is shown. DNA length standards are indicated along the left and right of the blots. (B) Quantitative representation of the mean telomere length (kb) calculated from A using TeloTool. Black bars indicate the range of telomere restriction fragments (TRFs) and the red dots represent the mean TRF length.