Table 2.
Subgroup analyses in pregnant cycles
| Letrozole | Cyclofenil | Clomifene | No medication | P value | |
|---|---|---|---|---|---|
| (n = 26) | (n = 75) | (n = 132) | (n = 64) | ||
| Age (years)* | 31.2 ± 3.0ab | 33.8 ± 3.9 | 33.9 ± 4.0 | 33.4 ± 4.2 | < 0.01 |
| BMI (kg/m2)* | 20.5 ± 3.6 | 20.4 ± 2.4 | 21.1 ± 2.8 | 20.4 ± 2.9 | NS |
| P4 (ng/mL) | |||||
| Mean* | 12.8 ± 4.1 | 12.0 ± 5.9a | 17.2 ± 9.0 | 12.8 ± 5.4c | < 0.01 |
| Median | 12.9 | 11.1 | 15.4 | 11.9 | NA |
| 5‰ P4 | 5.9 | 4.8 | 6.6 | 5.8 | NA |
| Lowest P4 | 4.6 | 2.3 | 3.7 | 5.0 | NA |
| E2 (pg/mL) | |||||
| Mean* | 127.7 ± 84.6a | 146.9 ± 80.6a | 241.8 ± 138.7 | 149.5 ± 56.9a | < 0.01 |
| Median | 106.8 | 133.1 | 203.3 | 140.1 | NA |
| 5‰ | 28.2 | 59.9 | 93.3 | 71.3 | NA |
| Lowest E2 | 23.4 | 44.2 | 70.2 | 71.1 | NA |
NS not significant, NA not available
* Values are indicated by means ± standard deviations. The Kruskal–Wallis H-test (two-sided) was used for comparisons among the four groups
aThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with clomifene group (P < 0.01)
bThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with cyclofenil group (P < 0.05)
cThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with clomifene group (P < 0.05)