Table 1.
Characteristics of patients receiving antibiotic prophylaxis with ceftriaxone and ampicillin (n = 4149)
| Characteristic | Ceftriaxone (n = 911) | Ampicillin (n = 3238) | p-value | ||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Age (yr) | |||||
| < 20 | 24 | 2.6 | 209 | 6.5 | |
| 20–34 | 691 | 75.9 | 2391 | 73.8 | |
| ≥ 35 | 196 | 21.5 | 638 | 19.7 | |
| Mean ± SD | 30.2 | ±5.3 | 28.9 | ±6.2 | < 0.001 |
| Ethnic minority | 130 | 14.3 | 1788 | 55.2 | < 0.001 |
| Education level | |||||
| None | 88 | 9.7 | 1513 | 46.7 | < 0.001 |
| Primary | 99 | 10.9 | 598 | 18.5 | |
| Intermediate | 236 | 25.9 | 673 | 20.8 | |
| College/higher | 488 | 53.5 | 454 | 14.0 | |
| Antenatal care | |||||
| No | 3 | 0.3 | 72 | 2.2 | < 0.001 |
| Camp | 40 | 4.4 | 827 | 25.5 | |
| Hospital | 868 | 95.3 | 2339 | 72.3 | |
| Body weight (kg) | |||||
| ≥ 80 | 155 | 17.0 | 408 | 12.6 | |
| Mean ± SD | 69.0 | ±11.7 | 65.4 | ±12.4 | < 0.001 |
| Hb (g/dL) | |||||
| < 11 | 145 | 15.9 | 617 | 19.1 | |
| Mean ± SD | 11.5 | ±1.0 | 11.4 | ±1.2 | 0.008 |
| HIV positive | 5 | 0.6 | 124 | 3.8 | < 0.001 |
| Referral | 48 | 5.3 | 1070 | 33.1 | < 0.001 |
| Gravida | |||||
| Primigravida | 308 | 33.8 | 1140 | 35.2 | |
| Median (IQR) | 2 | (1–2) | 2 | (1–3) | 0.002 |
| Multiple gestations | 13 | 1.4 | 123 | 3.8 | < 0.001 |
| GA (weeks) | |||||
| < 37 | 26 | 2.9 | 425 | 13.1 | |
| Mean ± SD | 38.6 | ±1.3 | 38.4 | ±2.4 | 0.152 |
| PV ≥5 occasions before surgery | 17 | 1.9 | 405 | 12.5 | < 0.001 |
| Amniotic fluid | |||||
| Clear | 896 | 98.4 | 2757 | 85.2 | < 0.001 |
| MSAF | 11 | 1.2 | 468 | 14.4 | |
| Foul smelling | 4 | 0.4 | 13 | 0.4 | |
| ROM duration (hr) | |||||
| Median (IQR) | 0 | (0–0) | 0 | (0–2.3) | < 0.001 |
| Fetal death | 5 | 0.6 | 38 | 1.2 | 0.136 |
| ASA score ≥ 3 | 19 | 2.1 | 198 | 6.1 | < 0.001 |
| Wound class ≥3 | 15 | 1.7 | 364 | 11.2 | < 0.001 |
| Operation time (min) | |||||
| ≥ 55 | 93 | 10.2 | 1209 | 37.3 | |
| Median (IQR) | 40 | (35–45) | 50 | (40–60) | < 0.001 |
| Emergency | 214 | 23.5 | 2487 | 76.8 | < 0.001 |
| EBL (mL) | |||||
| ≥ 500 | 121 | 13.3 | 1956 | 60.4 | |
| Median (IQR) | 300 | (300–400) | 500 | (400–500) | < 0.001 |
| UTI | 1 | 0.1 | 9 | 0.3 | 0.701 |
| Skin incision line | |||||
| Midline | 119 | 13.1 | 1492 | 46.1 | < 0.001 |
| Pfannelstein | 792 | 86.9 | 1746 | 53.9 | |
| Addition procedures | |||||
| Appendectomy/TR | 542 | 59.5 | 1432 | 44.2 | < 0.001 |
| Propensity score | |||||
| Mean ± SD | 0.86 | ±0.27 | 0.04 | ±0.11 | < 0.001 |
| Median (IQR) | 0.96 | (0.92–0.96) | 0.02 | (0.01–0.03) | < 0.001 |
ASA American Society of Anesthesiology, MSAF Meconium stained amniotic fluid, dL Decilitre, EBL Estimated blood loss, g Gram, GA Gestational age, Hb Hemoglobin, HIV Human immunodeficiency virus, hr. Hours, IQR Interquartile range, kg Kilogram, min Minute, PV Pelvic examinations, ROM Rupture of amniotic membranes, SD Standard deviation, SSIs Surgical site infections, TR Tubal resection, UTI Urinary tract infection, mL Millilitre, yr. Years