Table 1.
Correlation of MCM6 protein expression with clinicopathological parameters
| Characteristics | n | MCM6 | P value | |
|---|---|---|---|---|
| negative | positive | |||
| Age (years) | ||||
| ≤ 50 | 36 | 7 (19.4%) | 29 (80.6%) | 0.111 |
| > 50 | 34 | 12 (35.3%) | 22 (64.7%) | |
| Serum AFP (μg/l) | ||||
| ≤ 20 | 18 | 11 (61.1%) | 7 (38.9%) | 0.000 |
| > 20 | 52 | 8 (15.4%) | 44 (84.6%) | |
| HBsAg | ||||
| Negative | 8 | 5 (62.5%) | 3 (37.5%) | 0.035 |
| Positive | 60 | 15 (25.0%) | 45 (75.0%) | |
| GGT (U/I) | ||||
| ≤ 50 | 28 | 8 (28.6%) | 20 (71.4%) | 0.518 |
| > 50 | 42 | 11 (26.2%) | 31 (73.8%) | |
| Child-Pugh score | ||||
| A | 66 | 17 (25.8%) | 49 (74.2%) | 0.603 |
| B | 3 | 1 (33.3%) | 2 (66.7%) | |
| Tumor capsule | ||||
| No/incomplete | 61 | 16 (26.2%) | 45 (73.8%) | 0.463 |
| Complete | 9 | 3 (33.3%) | 6 (66.7%) | |
| Tumor differentiation | ||||
| I-II | 63 | 16 (25.4%) | 47 (74.6%) | 0.399 |
| III-IV | 5 | 2 (40.0%) | 3 (60.0%) | |
| Vascular invasion | ||||
| No | 63 | 19 (30.2%) | 44 (69.8%) | 0.097 |
| Yes | 7 | 0 (0%) | 7 (100%) | |
| Liver cirrhosis | ||||
| No | 31 | 14 (45.2%) | 17 (54.8%) | 0.003 |
| Yes | 39 | 5 (12.8%) | 34 (87.2%) | |
| Tumor size (cm) | ||||
| ≤ 5 | 34 | 11 (32.4%) | 23 (67.6%) | 0.247 |
| > 5 | 36 | 8 (22.2%) | 28 (77.8%) | |
| Tumor number | ||||
| Solitary | 49 | 18 (36.7%) | 31 (63.3%) | 0.004 |
| Multiple | 21 | 1 (4.8%) | 20 (95.2%) | |
| Early recurrence | ||||
| No | 36 | 15 (41.7%) | 21 (58.3%) | 0.002 |
| Yes | 33 | 3 (9.1%) | 30 (90.9%) | |
(P < 0.05) had been marked in boldface