Table 3.

Association statistics for methylation probes within the most significant differentially methylated region

Summary statistics						Probe expression		Annotation
Chromosome	Position (bp)	Probe	Coef.	SE	P value	β value	Change	Feature	Gene
11	20,625,538	cg07428491	−1.8326	0.8211	0.0208	0.5062	−0.0168	Shelf	SLC6A5
11	20,625,714	cg15083015	−1.7232	0.6336	0.0021	0.5019	−0.0318	Shelf	SLC6A5
11	20,625,992	cg04968806	−5.1739	1.7130	0.0013	0.5024	−0.0114	Shelf	SLC6A5
11	20,626,133	cg21957058	−1.6045	0.6913	0.0149	0.5045	−0.0209	Shelf	SLC6A5
11	20,626,264	cg09357935	−1.4053	0.4701	0.0009	0.5031	−0.0453	Shelf	SLC6A5
11	20,626,786	cg15828364	−2.1671	0.8315	0.0050	0.5062	−0.0209	Shelf	SLC6A5
11	20,627,025	cg23745839	−1.3968	0.5961	0.0146	0.5042	−0.0229	Shelf	SLC6A5
11	20,627,327	cg18042724	−2.7853	0.8116	0.0000	0.5069	−0.0374	Shelf	SLC6A5
11	20,627,597	cg14524936	−3.6597	1.0867	0.0002	0.5011	−0.0225	Sea	SLC6A5
11	20,627,781	cg19172170	−3.0185	1.0297	0.0016	0.5035	−0.0187	Sea	SLC6A5

Notes: Coef. denotes the regression coefficient, derived from a general linear model. A negative coefficient indicates lower probe expression in cases relative to controls. β value indicates the mean probe beta value, and change represents the mean difference in probe expression between cases and controls. Feature shows the position of each probe relative to CpG Islands—genomic regions in which the frequency of CpG sites is higher than other regions