. 2017 Dec 28;15(3):2985–2991. doi: 10.3892/ol.2017.7704

Table III.

Clinicopathological characteristics of HCC subtypes defined by AFP and CD133 expression.

	HCC subtype

Clinicopathological parameter	AFP⁻CD133⁻	AFP⁻CD133⁺	AFP⁺CD133⁻	AFP⁺CD133⁺	P-value
Age, years	47	33	28	19	0.526
≥50	35	25	20	11
<50	12	8	8	8
Sex					0.594
Male	38	25	25	15
Female	9	8	3	4
No. of tumor lesions					0.002^a
Solitary	41	22	24	9
Multiple	6	11	4	10
Cirrhosis					0.843
Absent	22	13	14	8
Present	25	20	14	11
Tumor size, cm					0.312
≥5	17	15	16	10
<5	30	18	12	9
Differentiation					0.018^a
Well/moderate	44	29	19	17
Poor	3	4	9	2
Vascular invasion					0.022^a
Absent	44	26	21	12
Present	3	7	7	7

P<0.05. HCC, hepatocellular carcinoma; AFP, α-fetoprotein.