Figure 2.

Silencing CCAT2 inhibited migration and invasion of EOC cells in vitro. (A) Representative images of the wound healing assay. (B) This assay showed that knockdown of CCAT2 reduced motility relative to NC cells. (C) Representative images of cell invasion was evaluated using a Matrigel invasion chamber. (D) Silencing CCAT2 inhibited invasion of SKOV3 and A2780 cells. The data represent the mean ± SD of three independent experiments. P<0.01 compared to NC group (Student's t-test). NC, negative control; siRNAs, small interfering RNAs; CCAT2, colon cancer-associated transcript 2.