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miR-106a targets PTEN. Seed sequence of miR-106a was identified in 3′ UTR of PTEN. The mutant seed sequence of PTEN 3′ UTR was also displayed (A). Luciferase activity in WT group was lower, while no significant change was discovered in mutant group (B). **P<0.01 miR-106a-3P vs. NC. PTEN, phosphatase and tensin homolog deleted on chromosome ten; 3′ UTR, 3′-untranslated region; WT, wild-type; NC, negative control; miR, microRNA.
