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miR-106a antagomiR upregulated PTEN protein level and downregulated p-PI3K/p-AKT protein levels. Western blot analysis showed that, there was no significant difference of the protein levels between control group and miR-NC antagomiR group, however, p-PI3K/p-AKT expression levels were obviously decreased and PTEN expression level was obviously increased by miR-106a antagomiR. miR, microRNA; NC, negative control; PTEN, phosphatase and tensin homolog deleted on chromosome ten.
