Table II.

Clinicopathological features according to KRAS codon status in 135 patients with metastatic colorectal cancer.

		KRAS codon 12			KRAS codon 13			KRAS codon 12 and 13
Parameter	No.	Wt	Mutation (n, %)	P-value	Wt	Mutation (n, %)	P-value	Wt	Mutation (n, %)	P-value
Sex				0.03a,b			>0.09c			0.04a,b
Male	85	69	16 (18.8)		78	7 (8.2)		62	23 (27.1)
Female	50	32	18 (36.0)		46	4 (8.0)		28	22 (44.0)
Age (years)d	58.2	57.7	59.8	0.34e	58.7	53.3	0.79e	58.3	58.1	0.65e
Body-mass indexd	22.9	23.1	22.5	0.30e	23.0	22.3	0.82e	23.2	22.4	0.26e
Location				0.44b			0.04c			0.51b
Right-sided	43	34	9 (20.9)		36	7 (16.3)		27	16 (37.2)
Left-sided	92	67	25 (27.2)		88	4 (4.3)		63	29 (31.5)
Metastasis				0.81b			0.74b			1.00b
Hepatic	42	32	10 (23.8)		38	4 (9.5)		28	14 (33.3)
Extrahepatic	93	69	24 (25.8)		86	7 (7.5)		62	31 (33.3)
Synchronous metastasis				0.71b			0.12b			0.58b
Yes	100	74	26 (26.0)		94	6 (6.0)		68	32 (32.0)
No	35	27	8 (22.9)		30	5 (14.3)		22	13 (37.1)

^aP<0.05

^bχ² test

^cFisher's exact test

^ddata presented as the mean

^eStudent's t-test. Wt, wild-type.