Table III.
Variable | Hazard ratio (95% confidence interval) | P-value |
---|---|---|
Sex | 0.17 | |
Male | Ref. | |
Female | 1.547 (0.832–2.875) | |
Age (years) | 1.012 (0.985–1.039) | 0.39 |
Location | 0.41 | |
Right-sided | Ref. | |
Left-sided | 0.758 (0.393–1.462) | |
Metastasis | 0.64 | |
Hepatic | Ref. | |
Extrahepatic | 1.194 (0.569–2.507) | |
Synchronous metastasis | 0.16 | |
Yes | Ref. | |
No | 0.633 (0.336–1.195) | |
Targeted drug | 0.85 | |
No | Ref. | |
Yes | 0.937 (0.479–1.834) | |
Neoadjuvant therapy | 0.78 | |
No | Ref. | |
Yes | 1.101 (0.569–2.129) | |
KRAS status | 0.04a | |
Wt | Ref. | |
Mutant | 1.884 (1.026–3.462) | |
Codon 12 status | <0.01 | |
Wt | Ref. | |
Mutant | 2.528 (1.369–4.668) | |
Codon 13 status | 0.49 | |
Wt | Ref. | |
Mutant | 0.657 (0.202–2.135) |
P<0.05. Ref., reference; wt, wild-type.