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. 2017 Dec 21;15(3):3024–3030. doi: 10.3892/ol.2017.7688

Table I.

Clinicopathological data of patients with hepatocellular carcinoma.

FXYD3 protein expression

Variables Cases, n Low, n (%) High, n (%) P-valuea
Age, years
  ≤50   70 43 (61.4) 27 (38.6) 0.231
  >50   67 34 (50.7) 33 (49.3)
Sex
  Male 124 69 (55.6) 55 (44.4) 0.775
  Female   13   8 (61.5)   5 (38.5)
Hepatitis B surface antigen
  Negative   69 39 (56.5) 30 (43.5) 0.604
  Positive   68 38 (55.9) 30 (44.1)
Serum AFP, µg/ml
  ≤400   86 47 (54.7) 39 (45.3) 0.722
  >400   51 30 (58.8) 21 (41.2)
Tumor size, cm
  ≤5   60 37 (61.7) 23 (38.3) 0.299
  >5   77 40 (51.9) 37 (48.1)
Tumor no.
  Single 100 63 (63.0) 37 (37.0) 0.011b
  Multiple   37 14 (37.8) 23 (62.2)
Microvascular invasion
  No 123 66 (53.7) 57 (46.3) 0.092
  Yes   14 11 (78.6)   3 (21.4)
Liver cirrhosis
  No   90 48 (53.9) 41 (46.1) 0.591
  Yes   47 28 (59.6) 19 (40.4)
Differentiation grade
  I+II   74 41 (55.4) 33 (44.6) 0.864
  III+IV   63 36 (57.1) 27 (42.9)
TNM stage
  I   88 55 (62.5) 33 (37.5) 0.051
  II+III+IV   49 22 (44.9) 27 (55.1)

AFP, α fetoprotein; TNM, tumor-node-metastasis; FYXD3, FXYD domain-containing ion transport regulator 3.

a

χ2 test.

b

P<0.05.