Table I.
Tumor volume and necrosis at different time points.
| P-value | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Categories | 3 days | 1 week | 2 weeks | 3 weeks | 4 weeks | p1 | p2 | p3 | p4 |
| Tumor volume (mm3) | 375.0±134.9 | 1,561.4±498.9 | 3,351.8±477.7 | 8,943.0±1,936.9 | 18,835.1±4,770.2 | – | – | – | – |
| Necrosis | |||||||||
| Number (n) | 0 | 2 | 9 | 27 | 29 | ||||
| Degree (necrosis area/total area, %) | 0 | 6 | 21 | 31.9 | 57.8 | 0.18 | 0.008 | <0.001 | <0.001 |
p1 was the comparison between the 3 days and 1 week groups; p2 was the comparison between the 1 and 2 week groups; p3 was the comparison between the 2 and 3 week groups; p4 was the comparison between the 3 and 4 week groups. Degree of necrosis (necrosis area/total area) was analyzed using the Friedman followed by post hoc analysis with Wilcoxon tests.