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Adenovirus Ad-Tp-E1A-Gp-p53 suppresses the growth of U251 cells. (A) Quantitative analysis of p53 expression via western blot analysis. β-actin gene was used as an internal control. (B) Inhibitory effect of Ad-Tp-E1A-Gp-p53 on the growth of U251 cells as detected by MTT. Data are presented as the mean ± standard deviation (n=3). *P<0.05. Group 1, 1 MOI; group 2, 10 MOI; group 3, 100 MOI; group 4, 1,000 MOI. MOI, multiplicity of infection. E1A, early viral 1A.
