Serum concentrations of IL-6 and TNF-α. (A) Sham; (B) AP; (C) Sham+Rut (100 µg/kg); (D) AP+Rut L (30 µg/kg); (E) AP+Rut M (100 µg/kg); (F) AP+Rut H (300 µg/kg); (G) Sham+Cap; (H) AP+Cap; (I) AP+Cap+Rut (100 µg/kg); (J) AP+Sol. Results are presented as the mean ± standard deviation. (n=10). #P<0.05 vs. (B), (D-F) and (H-J); @P<0.05 vs. (B); *P<0.05. IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; AP, acute pancreatitis; Rut, rutaecarpine; Cap, capsazepine.