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. 2017 Dec 18;15(3):3287–3294. doi: 10.3892/ol.2017.7633

Figure 3.

Figure 3.

DACT2 inhibits the proliferation and invasion of breast cancer cells. (A) Detection of the overexpression of DACT2 in MDA-MB-468 cells. (B) Enforced expression of DACT2 in MDA-MB-468 cells inhibits cell proliferation. (C) Enforced expression of DACT2 in MDA-MB-468 cells inhibits cell invasion. (D) 5-Aza treatment inhibits the proliferation of cells. (E) 5-Aza treatment inhibits the invasion of cells. (F) Knockdown the expression of DACT2 in MDA-MB-231 cells by siRNA. (G) Repression of DACT2 promotes the proliferation of MDA-MB-231 cells. (H) Repression of DACT2 promotes the invasion of MDA-MB-231 cells. DACT2, dishevelled-associated antagonist of β-catenin homolog 2; 5-Aza, 5-azacytidene; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; NC, negative control; siRNA, small interfering RNA.