Table I.
Clinical and demographic characteristics of patients and controls.
| Characteristic | Patients, n=285 (%) | Controls, n=257 (%) |
|---|---|---|
| Age, years (mean ± SDa) | 47.3±9.5 | 47.1±8.7 |
| Tumor stage | ||
| I | 70 (24.8) | |
| II | 141 (49.6) | |
| III | 63 (21.8) | |
| IV | 11 (3.8) | |
| Labor presentation | ||
| Eutocia | 237 (83.2) | 182 (70.8) |
| Caesarean section | 48 (16.8) | 75 (29.2) |
| Histological type | ||
| Squamous cell carcinoma | 236 (82.9) | |
| Adenocarcinoma | 39 (13.7) | |
| Other | 10 (3.4) | |
| Parity | ||
| Never | 10 (3.5) | 15 (5.8) |
| 1 | 132 (46.6) | 159 (61.9) |
| 2 | 94 (32.9) | 56 (21.8) |
| 3 | 36 (12.6) | 19 (7.4) |
| ≥4 | 13 (4.4) | 8 (3.1) |
| Abortion frequency | ||
| Never | 98 (34.4) | 112 (43.6) |
| 1 | 49 (17.2) | 51 (19.8) |
| 2 | 53 (18.6) | 57 (22.2) |
| ≥3 | 85 (29.8) | 37 (14.4) |
| Oral contraceptive pill use | ||
| Never | 239 (83.8) | 235 (91.4) |
| Ever | 46 (16.2) | 22 (8.6) |
| Liquor and tobacco | ||
| Never | 177 (62.1) | 168 (65.4) |
| Ever | 108 (37.9) | 89 (34.6) |
| Menopausal status | ||
| Premenopausal | 205 (71.9) | 187 (72.7) |
| Postmenopausal | 80 (28.1) | 70 (27.3) |
| Blood type | ||
| O | 54 (18.9) | 49 (19.1) |
| A | 95 (33.3) | 78 (30.3) |
| B | 116 (40.7) | 85 (33.1) |
| AB | 20 (7.1) | 45 (17.5) |
| HPV genotypesb | ||
| Negative | 79 (27.7) | 198 (77.0) |
| 16 or 18 | 158 (55.5) | 31 (12.1) |
| Othersc | 48 (16.8) | 28 (10.9) |
| BMI | ||
| <18.5 | 6 (2.1) | 5 (1.9) |
| 18.5–23.9 | 203 (71.2) | 211 (82.1) |
| ≥24 | 76 (26.7) | 41 (17.0) |
| Family history of cancer | ||
| No | 220 (77.1) | 223 (86.8) |
| Yes | 65 (22.9) | 34 (13.2) |
a
Age at first diagnosis
b
HPV genotypes were determined by a Cobas HPV Test (Roche Molecular Systems, Inc., Alameda, CA, USA)
c
HPV genotypes 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68. HPV, human papillomavirus; BMI, body mass index.