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. Author manuscript; available in PMC: 2018 Jan 23.
Published in final edited form as: Nature. 2017 Jul 10;547(7663):364–368. doi: 10.1038/nature22988

Figure 2. K2P2.1(TREK-1) activator interactions.

Figure 2

Cartoon diagram of a, K2P2.1(TREK-1):ML335 and b, K2P2.1(TREK-1):ML402 interactions. Electrostatic and hydrogen bond interactions are black. Cation-π and π-π interactions are grey. c, and d, comparison of K2P2.1(TREK-1) (smudge) with c, K2P2.1(TREK-1):ML335 (deep salmon) and d, K2P2.1(TREK-1):ML402 (cyan).