Table II.

Association between clinicopathological factors and HOXA9 protein expression as determined by immunohistochemistry.

		HOXA9 IHC, n
Characteristics	Total	Positive	Negative	P-value
Total	231	161	70
Age				1.00
≥60 years	174	121	53
<60 years	57	40	17
Gender				0.77
Male	136	96	40
Female	95	65	30
Stage				0.03
0	5	4	1
I	37	25	12
II	85	52	33
III	66	52	14
IV	38	28	10
Tumor location				0.65
Colon	165	113	52
Rectum	66	48	18
Histology				0.82
tub	203	142	61
por	28	19	9
Depth				0.28
T1	28	19	9
T2	27	22	5
T3	159	106	53
T4	17	14	3
Lymphatic invasion				1.00
Absent	48	34	14
Present	183	127	56
Venous invasion				0.60
Absent	50	33	17
Present	181	128	53
Lymph node metastasis				0.02
Negative	135	86	49
Positive	96	75	21
Liver metastasis				1.00
Negative	200	139	61
Positive	31	22	9

P-values were calculated using Fisher's exact test or a χ² test, where appropriate. T, tumor; HOX, homeobox; tub, tubular adenocarcinoma; por, poorly differentiated adenocarcinoma.