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. 2017 Dec 29;7(1):e006656. doi: 10.1161/JAHA.117.006656

Figure 2.

Figure 2

The effect of rs6078905 polymorphism on the blood pressure response of whites and blacks treated with hydrochlorothiazide in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) study. Blood pressure responses were adjusted for baseline blood pressure, age, sex, and population substructure, and P values represented are for contrast of adjusted means between different genotype groups. Error bars represent SEM. DBP indicates diastolic blood pressure; HCTZ, hydrochlorothiazide; SBP, systolic blood pressure; SPTLC3, serine palmitoyltransferase, long chain base subunit 3 (A) Diastolic blood pressure response in PEAR white participants, (B) Systolic blood pressure response in PEAR white participants, (C) Diastolic blood pressure response in PEAR black participants, (D) Systolic blood pressure response in PEAR black participants.