Table 1.
Description of the Analytical Sample (n=648): CARDIA Brain MRI Substudy
| Characteristic | Value |
|---|---|
| Demographic characteristics | |
| Age at year 5, y | 30.4±3.5 |
| Age at year 25, y | 50.4±3.5 |
| Women, n (%) | 339 (52) |
| Black, n (%) | 244 (38) |
| Education, y | 15.0±2.3 |
| Cardiac parameters | |
| LVEF, % (n=297) | 62.8±7.4 |
| LAV, mL/m2 (n=406) | 16.1±4.2 |
| LV mass, g/m2 (n=627) | 79.9±18.4 |
| Brain measures | |
| WMFA | 0.3±0.02 |
| Gray matter volume, cm3 | 518.5±53.7 |
| White matter volume, cm3 | 467.0±59.5 |
| Total brain volume, cm3 | 985.5±107.2 |
| AWM volume, n (%) | |
| None | 127 (20) |
| Little (≤0.3 cm3) | 246 (38) |
| High (>0.3 cm3) | 275 (42) |
| Covariates | |
| Systolic blood pressure, mm Hg | 117.2±14.3 |
| Diastolic blood pressure, mm Hg | 72.7±10.6 |
| Total cholesterol, mg/L | 193.2±35.3 |
| Fasting plasma glucose, mg/L | 96.4±28.8 |
| BMI | 28.7±5.7 |
| Sedentary behavior, h/d | 6.8±4.0 |
| Alcohol intake, mL/d, median (IQR) | 4.8 (0.0–17.0) |
| APOE ɛ4 allele, n (%) | 178 (29) |
| Smoker, n (%) | |
| Never | 393 (61) |
| Current | 95 (15) |
| Former | 153 (24) |
Data are presented as mean±SD unless otherwise noted. The information about cardiac parameters comes from year 5, and all other data come from year 25. AWM indicates abnormal white matter; BMI, body mass index; CARDIA, Coronary Artery Risk Development in Young Adults; IQR, interquartile range; LAV, left atrial volume; LV mass, left ventricular mass; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging; WMFA, white matter fractional anisotropy.