Figure 1.

Study design. A, Two array analyses were performed in the identification cohort: ruptured (rAAA) vs stable and intermediate (≤55 mm) vs large (>70 mm) size AAA. The Venn diagram above depicts the overlap among the different groups in the identification cohort. The Venn diagrams underneath show the overlap among the identified differentially expressed transcripts of the 2 analyses. An independent validation cohort was used to validate the overlapping candidate genes from the array analyses with quantitative real‐time PCR. B, Volcano plot of differentially expressed transcripts for eAAA vs rAAA array analysis. C, Volcano plot of differentially expressed transcripts for intermediate vs large AAA array analysis (colored dots, |log₂ FC| ≥1.5, adjusted P<0.05). AAA indicates abdominal aortic aneurysm; eAAA, elective AAA; iAAA, intermediate AAA; lAAA, large AAA; qRT‐PCR, quantitative real‐time polymerase chain reaction; rAAA, ruptured AAA.