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. 2017 Nov 30;6(12):e006798. doi: 10.1161/JAHA.117.006798

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© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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HIF‐1α strongly associates with differentially expressed genes in rAAA. Results from the Ingenuity pathway analysis (stable vs ruptured AAAs) for the activated upstream regulator HIF‐1α (activation z‐score 4.329 and an overlap P value of 2.74×10⁻²²) showing the significantly up‐ (red) and downregulated (green) genes and their localization in the cell. Figure ©2000‐2016 by Qiagen (Hilden, Germany). Reproduced with permission.