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. 2017 Dec 22;6(12):e006809. doi: 10.1161/JAHA.117.006809

Table 1.

Influence of IR, IPC, and IPoC on β‐AR–Mediated Effects 2 Hours After Myocardial Infarction

Heart Rate (beats/min)
Baseline ISO
Nx 244±44 318±26a
IR 234±42 305±48a
IPC 246±24 314±52a
IPoC 230±60 303±36a
Perfusion Pressure (mm Hg)
Baseline ISO
Nx 57±8 46±3a
IR 64±8 55±7a
IPC 62±13 50±7a
IPoC 72±18 62±14a
LVDP (mm Hg)
Baseline ISO
Nx 109±18 126±7a
IR 85±13 98±12a
IPC 91±20 100±22a
IPoC 94±24 93±21

The heart rate increased and the perfusion pressure fell uniformly under ISO stimulation in all 4 treatment groups. A significant increase in the LVDP was observed only in hearts of the Nx, IR, and IPC groups. Data are means±SD of n=6 to 8 hearts.

IPC indicates ischemic preconditioning; IPoC, ischemic postconditioning; IR, ischemia/reperfusion; ISO, isoproterenol; LVDP, left ventricular developed pressure; Nx, normoxia.

a

P≤0.05 vs baseline.