Table 1.
Patient Characteristics
| Characteristics | PH Group (n=35) | Control Group (n=10) | P Value |
|---|---|---|---|
| Age, y | 61±9 | 57±9 | 0.3092 |
| Female sex, n (%) | 21 (60) | 7 (70) | … |
| BSA, m2 | 1.79±0.24 | 1.87±0.25 | 0.3979 |
| mPAP, mm Hg | 36.4±11.0 | … | … |
| PVR, WU | 8.5±6.4 | … | … |
| PAWP, mm Hg | 11.7±3.9 | … | … |
| WHO classification, n (%) | |||
| Class I | 16 (46) | … | … |
| Class III | 16 (46) | … | … |
| Class V | 3 (8) | … | … |
| 6‐MWT | 328±96 | … | … |
| NT‐proBNP, ng/L | 420 (243–1879) | … | … |
| BNP, ng/L | 44 (16–122) | … | … |
| RVEDV, mL | 165±68 | 112±28 | 0.0011 |
| RVESV, mL | 101±68 | 46±15 | <0.0001 |
| RVSV, mL | 63±20 | 66±16 | 0.6230 |
| RV mass index, g/m2 | 34±11 | 16±7 | <0.0001 |
| RVEF, % | 43±15 | 59±5 | <0.0001 |
| VVCR | 1.87±1.51 | 0.69±0.17 | <0.0001 |
| RVCO, L/min | 3.5±1.4 | 3.7±0.8 | 0.4278 |
| HR, bpm | 54±18 | 57±7 | 0.5203 |
| MPA Vmax, m/s | 0.61±0.24 | 0.82±0.26 | <0.0001 |
| RPA Vmax, m/s | 0.58±0.21 | 0.85±0.13 | <0.0001 |
| MPA size, cm | 3.5±0.4 | 2.3±0.4 | <0.0001 |
| RPA size, cm | 2.5±0.4 | 1.7±0.2 | <0.0001 |
| MPA RAC, % | 29±5 | 16±5 | <0.0001 |
Data are reported as mean±SD or median (interquartile range) unless otherwise indicated. 6‐MWT indicates 6‐minute walk test; BNP, brain natriuretic peptide; BSA, body surface area; HR, heart rate; MPA, main pulmonary artery; mPAP, main pulmonary arterial pressure; NT‐proBNP, N‐terminal pro‐B‐type BNP; PAWP, pulmonary arterial wedge pressure; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; RAC, relative area change; RPA, right pulmonary artery; RV, right ventricular; RVCO, RV cardiac output; RVEDV, RV end‐diastolic volume; RVEF, RV ejection fraction; RVESV, RV end‐systolic volume; RVSV, RV stroke volume; Vmax, maximum velocity; VVCR, ventricular/vascular coupling ratio; WHO, World Health Organization; and WU, Wood unit.